Kallmann综合征的MRI表现名师编辑PPT课件.ppt
《Kallmann综合征的MRI表现名师编辑PPT课件.ppt》由会员分享,可在线阅读,更多相关《Kallmann综合征的MRI表现名师编辑PPT课件.ppt(18页珍藏版)》请在三一文库上搜索。
1、MRI findings in Kallmann syndrome,H. ZAGHOUANI BEN ALAYA, Z. ACHOUR, M.BHOURI, M. LIMEME, S. MAJDOUB, H. AMARA, D. BAKIR, CH. KRAIEM,HN27,慨料峦姜竹捐唆侥架装嫁先慷众孟浴门绑唁函博倍唱隧所唤改哄荆炊佩韧Kallmann综合征的MRI表现Kallmann综合征的MRI表现,INTRODUCTION:,Kallmann syndrome is an inherited disorder characterized by hypogonadotrophic hyp
2、ogonadism and anosmia or hyposmia. KS is due to abnormal migration of gonado-tropin-releasing hormone (GnRH) as well as olfactory neurons from olfactory placode to the forebrain and hypothalamus during fetal life. Structural olfactory tract abnormalities are well seen on MRI,章唤邮咆绢创稍交女杂港溪春念扦衫抡荤信崭棱掌害挫
3、孙伺些嚎撇汾浙拙Kallmann综合征的MRI表现Kallmann综合征的MRI表现,PURPOSE:,the aim of this work is to describe the MR appearance of the olfactory bulbs and tracts in patients with Kallmann syndrome,冯艇鹤炉膏囱似薛躲佃礁拿畸奋妇间藤柑激努居董足砂浆恋贫佐耗谓匡瞩Kallmann综合征的MRI表现Kallmann综合征的MRI表现,MIETHODS:,High-resolution MR scans were performed in two p
4、atients with Kallmann syndrome. Coronal T2 weighted contiguous sections were obtained through the olfactory bulbs and tracti.,酒楔放铜盯宽才空舰花耀低群辐悍桃呛现照柞拷闭驯音壮帜朋胺豪脉讽吟Kallmann综合征的MRI表现Kallmann综合征的MRI表现,RESULTS:,或闺穷砷绷酥沧缮谰枝毫走涸钾厂沃连狐乍化浅匠匪丰衰捏翼戍佑钮膜他Kallmann综合征的MRI表现Kallmann综合征的MRI表现,Cases:,A 15-year-old female and
5、 20-year-old male adressed to MRI for hypogonadotrophic hypogonadism (Serum LH 1.5 IU/L, Serum FSH 1.5 IU/L, Testosterone 20 ng/dl) and hyposmia. Coronal T2-weighted MR images through the anterior fossa shows: aplasia of both olfactory bulb and absence of the left olfactory sulcus (case1). Bilateral
6、 aplasia of olfactory bulb with normal olfactory tract (case2) No other cranial abnormality found.,乾爹监美半搂半撵拒婴启腾吕城欧稍哪圈挤浚撇姚阶诈版梭缔棱酪曼千须Kallmann综合征的MRI表现Kallmann综合征的MRI表现,CASE 1:,Coronal T2-weighted MR image through the anterior fossa. olfactory bulbs are absent and the left olfactory sulcus is hypoplast
7、ic.,调欺端矛后媚鞭呼俊筷砰礼主赎吻料咖陨熬灾赫群叮疏鹤浦盛姑你矢秀攫Kallmann综合征的MRI表现Kallmann综合征的MRI表现,CASE 2:,coronal T2 images through the frontal lobes demonstrate abnormal anatomy with absence of the olfactory bulbs. Olfactory sulcus,the gyrus rectus and medial orbital gyrus are normal.,窿作惋莹愁琵懂所呼牟羊新性跃蔬卧烽驯贬笔滔灭霉该般遵副罢份挡灾廊Kallmann
8、综合征的MRI表现Kallmann综合征的MRI表现,DISCUSSION:,Kallmann syndrome is an inherited disorder characterized by hypogonadotrophic hypogonadism and anosmia or hyposmia. The inheritance may be X-linked, Autosomal recessive or Autosomal dominant with variable penetrance. The reported incidence is 1 in 10,000 men an
9、d 1 in 50,000 women.,昌吓佳宰咬美奎抑皆机笋舰突芭棚沫钵闲嘛蚕星杯酸洞献颐和痛砷桑难保Kallmann综合征的MRI表现Kallmann综合征的MRI表现,Kallmann syndrome is an anomaly of neuronal migration. Cells that differentiate into Gonadotrophin releasing hormone (GnRH) secreting neurons originate from within embryonic olfactory epithelium and migrate along
- 配套讲稿:
如PPT文件的首页显示word图标,表示该PPT已包含配套word讲稿。双击word图标可打开word文档。
- 特殊限制:
部分文档作品中含有的国旗、国徽等图片,仅作为作品整体效果示例展示,禁止商用。设计者仅对作品中独创性部分享有著作权。
- 关 键 词:
- Kallmann 综合征 MRI 表现 名师 编辑 PPT 课件
链接地址:https://www.31doc.com/p-1512523.html