2019早产儿注射促红细胞生成素对贫血的防治效果及护理.doc
《2019早产儿注射促红细胞生成素对贫血的防治效果及护理.doc》由会员分享,可在线阅读,更多相关《2019早产儿注射促红细胞生成素对贫血的防治效果及护理.doc(9页珍藏版)》请在三一文库上搜索。
1、DOC格式论文,方便您的复制修改删减早产儿注射促红细胞生成素对贫血的防治效果及护理(作者:_单位: _邮编: _) 【摘要】 目的 观察重组人类促红细胞生成素(recombinant human erythropoietin,rh-EPO)对早产儿贫血的防治效果。方法 将早产后在我科住院的胎龄小于34周,体质量低于2000 g的新生儿50例,按入院顺序随机分成两组,治疗组25例,对照组25例。两组患儿入院后常规给予保暖,维持体温、血糖、血压等内环境稳定,营养支持等处理,必要时输血。治疗组于生后第7天开始给予重组人类促红细胞生成素200 IU/(kgd),皮下注射,每周3次,共4周。对照组仅用常
2、规治疗。分别于生后第1、2、3、4、5周抽取外周静脉血,检测并比较不同时间两组早产儿的血红蛋白(haemoglobin,Hb)、网织红细胞(reticulocyte,Ret)和血细胞比容(hematocrit,HCT)。结果 两组早产儿出生后血红蛋白均下降,但治疗组下降缓慢,治疗结束后两组差异非常显著(P001);治疗组治疗后网织红细胞计数和血细胞比容较对照组明显升高(P001);治疗结束后两组网织红细胞计数差异缩小(P005),但血细胞比容差异仍显著(P001);治疗组的输血率(8%)较对照组的输血率(32%)明显减少(P005)。结论 重组人类促红细胞生成素可以有效的防治早产儿贫血,减少输
3、血。 【关键词】早产儿;贫血;重组人类促红细胞生成素 【Abstract】 Objective To discuss the effect of recombinant human erythropoietin(rh-EPO)in prevention and treatment of anemia of prematurity.Methods 50 preterm infants who admitted hospital after premature delivery were randomly enrolled in this study:treated group(25 neonat
4、es)and control group(25 neonates),theirs gestation ages less than 34 weeks and the birth weight less than 2000 g.They were routinely kept body warm,serum glucose and blood pressure in normal levels and were nutritional supported,sometimes,the blood transfusion are introduced.rh-EPO 200 IU/(kgd)was g
5、iven to the treated group thrice-weekly by subcutaneous injection,one time every 2 days for 4 weeks from the lst week of life.The control group is simple routinely treated.The level of serum haemoglobin(HB),hematocrit(HCT)and reticulocyte(Ret)were detected on lst week,2nd week,3rd week,4th week and
6、5th week after birth.Results The levels of HB in both of these two groups are decreased,but the speed of decreasing in the treated group is slower than the control group,the difference is significant between the two groups to the treatment end(P001).The HCT and Ret of treated group were increased si
7、gnificantly compared with control group(P001).To the end,the difference of Ret is small(P005),but the difference of HCT is still obvious between the two groups(P001).The need for transfusion in the treated group was significantly less than that in the control group(P005).Conclusion rh-EPO can effici
8、ently prevent and treat anemia of prematurity and decrease the need for transfusion. 【Key words】Premature infant; Anemia; Recombinant erythropoietin 早产儿贫血是临床比较常见的现象,所有早产儿出生数天后都会出现外周血红细胞和血红蛋白(haemoglobin,Hb)的下降,体质量越低,红细胞和血红蛋白的降低发生愈早,持续时间越长。这给早产儿带来了显著的负面影响,它可导致生长迟滞、易患感染性疾病、发育迟缓,并有增加死亡率的风险。红细胞生成素水平及其对贫
9、血的反应低下是导致早产儿贫血的主要原因之一1。因此,本研究在常规治疗的基础上,给予早产儿皮下注射重组人类促红细胞生成素(recombinant human erythropoietin,rh-EPO)以预防和治疗早产儿贫血,取得较好的效果。现报告如下。 1 资料和方法 11 病例选择 选择2006年10月至2008年5月在我科住院的早产儿50例,按入院顺序分成治疗组25例,对照组25例。其中男31例,女19例,胎龄3034周,出生体质量11002000 g。所有病例出生时均无贫血,失血史,无红细胞增多症,病程中未发现溶血及血液系统疾病。 12 方法 所有早产儿入院后均常规给予暖箱保暖,维持体温
- 配套讲稿:
如PPT文件的首页显示word图标,表示该PPT已包含配套word讲稿。双击word图标可打开word文档。
- 特殊限制:
部分文档作品中含有的国旗、国徽等图片,仅作为作品整体效果示例展示,禁止商用。设计者仅对作品中独创性部分享有著作权。
- 关 键 词:
- 2019 早产儿 注射 红细胞 生成 贫血 防治 效果 护理
链接地址:https://www.31doc.com/p-2468721.html