第二节糖酵解glycolysis.ppt
《第二节糖酵解glycolysis.ppt》由会员分享,可在线阅读,更多相关《第二节糖酵解glycolysis.ppt(40页珍藏版)》请在三一文库上搜索。
1、第二节 糖酵解 glycolysis,Louis Pasteur in his laboratory,一. 糖酵解的概念,指葡萄糖通过一系列步骤,降解成三碳化合物(丙酮酸)的过程。,糖酵解途径又称 EMP途径 (Embden-Meyerhof Parnas pathway),定义,一. 糖酵解的概念,Glucose occupies a central position in the metabolism of plants, animals, and many microorganisms. It is relatively rich in potential energy, and thu
2、s a good fuel; the complete oxidation of glucose to carbon dioxide and water proceeds with a standard free-energy change of 2,840 kJ/mol.,定义,一. 糖酵解的概念,Glucose is not only an excellent fuel, it is also a remarkably versatile precursor, capable of supplying a huge array of metabolic intermediates for
3、biosynthetic reactions. A bacterium such as Escherichia coli can obtain from glucose the carbon skeletons for every amino acid, nucleotide, coenzyme, fatty acid, or other metabolic intermediate it needs for growth.,一. 糖酵解的概念,In glycolysis (from the Greek glykys, meaning “sweet,” and lysis, meaning “
4、splitting”), a molecule of glucose is degraded in a series of enzyme-catalyzed reactions to yield two molecules of the three-carbon compound pyruvate. derive most of their energy from glycolysis; many anaerobic microorganisms are entirely dependent on glycolysis.,二. 糖酵解的过程,第一步:葡萄糖的磷酸化,第一阶段,激酶:催化将ATP
5、上的磷酸基团转移到受体上的酶。激 酶都需要Mg2+作为辅助因子。,二. 糖酵解的过程,第一步:葡萄糖的磷酸化,第一阶段,二. 糖酵解的过程,二. 糖酵解的过程,第二步:6-磷酸果糖的生成,第一阶段,二. 糖酵解的过程,第二步:6-磷酸果糖的生成,第一阶段,二. 糖酵解的过程,第三步:1, 6-二磷酸果糖的生成,第一阶段,磷酸果糖激酶(PFK)是EMP途径的关键酶,其活性大小控制着整个途径的进程。,二. 糖酵解的过程,第三步:1, 6-二磷酸果糖的生成,第一阶段,磷酸果糖激酶(PFK)是EMP途径的关键酶,其活性大小控制着整个途径的进程。,二. 糖酵解的过程,Phosphofructokinas
- 配套讲稿:
如PPT文件的首页显示word图标,表示该PPT已包含配套word讲稿。双击word图标可打开word文档。
- 特殊限制:
部分文档作品中含有的国旗、国徽等图片,仅作为作品整体效果示例展示,禁止商用。设计者仅对作品中独创性部分享有著作权。
- 关 键 词:
- 第二 酵解 glycolysis
链接地址:https://www.31doc.com/p-2560199.html