经皮植入记忆合金自体膨胀支架体外研究.ppt
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1、2019/5/20,2008 CSIR Beijing Hongjian SHI,Implantation of Endothelial Progenitor Cells on a Self-expanding Metal Stent: an in vitro Study,Hongjian Shi,MD Gaojun Teng,Ph.D,MD Aihong Cao,MD Deparment of Radiology, Zhongda Hospital, Southeast Universty,2019/5/20,2008 CSIR Beijing Hongjian SHI,Content,Ba
2、ckground Materials and methods Results Discussion,2019/5/20,2008 CSIR Beijing Hongjian SHI,Background,Restenosis:pseudointimal hyperplasia ( PTA, stent) High restenosis in TIPS(30%-50%, 1y) Bile leakage unavoidable during TIPS Bile inhibit both SMC and EC Covered Viattor stent 1. Coldwell D, Radiolo
3、gy 1995 2. Zhuang Z,AJR 2002 3. LaBerge J,JVIR 1993 4. Nishimine K,Radiology 1995 5. Teng G,Radiology 1998;2005 6. Cejna M,Radiology 2001 7. Hausegger K,JVIR 2004,2019/5/20,2008 CSIR Beijing Hongjian SHI,Background,EPC(endothelial progenitor cell) can differentiate into EC(endothelial cell) and inco
4、rporate into sites of active angiogenesis. Asahara, Science 1997,2019/5/20,2008 CSIR Beijing Hongjian SHI,Shantsila E, et al.JACC 2007,2019/5/20,2008 CSIR Beijing Hongjian SHI,Zammarettia P, Int J Biochem Cell Biol 2005; 37: 493-503.,2019/5/20,2008 CSIR Beijing Hongjian SHI,EPC Isolation,Culture,Ide
5、ntification,Healthy domestic farm swine(25kg) Density gradient centrifugation Culture medium- EGM-2 Cell markers CD34, VEGFR-2, Vwf Specific function: uptaken DiI-AC-LDL,and binding FITC-UEA-1 Ben-Shoshan, PharmacologyTherapeutics 2007,2019/5/20,2008 CSIR Beijing Hongjian SHI,Representative relative
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- 关 键 词:
- 植入 记忆 合金 膨胀 支架 体外 研究
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