高血压联盟与转化医学课件.ppt
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1、高血压联盟与转化医学,刘力生,Purpose of WHL,To develop or promote health by educating and instructing health care professionals and the public on preventative and curative measures for hypertension. 对专业人员和群众进行 健康促进教育 To promote and conduct research related to the prevention and treatment of hypertension 促进和组织防治高血
2、压的研究项目 To promote the detection, control and prevention of hypertension in the population through joint efforts of all national leagues and societies. 联合各国的联盟与学会促进高血压防控工作 To liaise with the national bodies, promoting the exchange of information among them, and offering internationally applicable met
3、hods and programs for hypertension control. 与各国家团体联系,交流提供有关控制高血压的国际可行的方法与计划.,转化医学与中国高血压联盟,转化医学是本世纪从循证医学发展而形成的一个医学实践和干预性流行病学的理念,它融汇基础科学、社会科学、政治科学于一体,兼顾治病和预防,其涵盖的领域已超出现行医疗保健服务的范畴。 From bench to bedside to population(实验室临床社区) 转化医学研究可分为: 1期:基础实验研究 2期:基础研究应用于临床: 临床试验,中国高血压指南 3期:改变环境与政策层面的因素才能做到临床公共卫生和预防措
4、施的可持续发展。健康促进与社区防治,Hypertension Clinical Trials 中国临床试验的经验 Liu Lisheng,Chronic Disease in China -2007 CVD Report of China 中国慢病现状,New onset stroke: 2million/yr,Survived stroke:13 million CVD patients: 230 million New onset MI: 0.5 million,survived MI: 3 million;CHD: 8 milllion Patients with chronic dis
5、eases in 2003: 574 million : DM: 33 million- Cancer: 46 million Cerebrovascular diseases: 93 million Cardiac disease: 165 million Hypertension: 237 million,Hypertension Clinical Trials in China,International Trials,International Trials,International Trials,Experience (1/2),Easier to recruit particip
6、ants from clinics or communities. Concommitant drug treatment are less. large simple trials are feasible in China.,Example:Chinese subjects in HYVET (40% of total sample),Slightly younger, lighter & shorter. Smoked more but drank less alcohol. Less previous episodes of MI, more previous stroke Had l
7、ower blood urea, uric acid and Cr , higher HDLC. Blood glucose & TC , Na & K, blood haematocrit & Hb were all lower. Much easier to recruit, less concomitant tr. More compliant to tr. Easier to FU.,Experience (2/2),CHL was established on top of Syst.-China & PATs Collaborative group (31 medical univ
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- 高血压 联盟 转化 医学 课件
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