牛磺酸对糖尿病大鼠视网膜神经胶质原纤维酸性蛋白MRNA及其蛋白表达的影响.pdf
《牛磺酸对糖尿病大鼠视网膜神经胶质原纤维酸性蛋白MRNA及其蛋白表达的影响.pdf》由会员分享,可在线阅读,更多相关《牛磺酸对糖尿病大鼠视网膜神经胶质原纤维酸性蛋白MRNA及其蛋白表达的影响.pdf(4页珍藏版)》请在三一文库上搜索。
1、Effect of ta()*+, o+ t-, ,./),00*o+ of ),t*+a1 21*a1 f*3)*11a)4 ac*5*c /)ot,*+ 6789 a+5 *t0 /)ot,*+ *+ )at0 :*t- 5*;3,t,0 6,11*t(0! BASIC RESEARCH !“ #$%0=an?7A180Bans= Cro4in3e0CDinaE FGao;in2 H3Dool of 5eIei Je;i3al Kni4ersitL0Gao;in2M?1MMM,5eIei Cro4in3e0CDinaE N;=lt Class of Clini3al Je;i3ineO 5
2、eIei Je;i3al Kni4ersitL05an;an M7MM1?,5eIei Cro4in3e0 CDina !“ 6$%0 Pi=an?7M180 Bans= Cro4in3e0 CDina 7,c,*9?ABCD8E=DiaIeti3 retinopatDL is tDe 3ommon 3ompli3ations of ;iaIetes mellit=sW Xa=rine is free aminoa3i; YitD tDe mostlL aI=n;ant 3on: tent in retinaOan; it is tDe ne3essarL n=trition fa3tor f
3、or re2eneration an; ;e4elopment of retinaW Defi3ien3L of ta=rine Yill 3a=se str=3t=ral an; f=n3: tional 3Dan2e of retinaW CFG?HIJG=Xo proIe into tDe effe3t of ta=rine on tDe eZpression of retinal 2lial fiIrillarL a3i;i3 protein RBNCV mN EGKIA8= N ran;omie; an; 3ontrolle; oIser4ation KGHHI8A= XDir; J
4、ilitarL Je;i3al Kni4ersitL of CDinese C1N L9HGBI9MK=XDis eZperiment Yas 3arrie; o=t at tDe XDir; JilitarL Je;i3al Kni4ersitL of CDinese C1N from Jar3D FMM to De3emIer FMMW XotallL 7S 3lose; 2ro=p HD ratsOYitD Io;L mass of F7M 2OYere 3DosenW XDe s=33essf=l ;iaIeti3 rat mo;el Yere ran;omlL ;i4i;e; int
5、o 9 2ro=ps_ ;i: aIeti3 2ro=p of 1 montDO ta=rine:treate; ;iaIeti3 2ro=p of 1 montDO ;iaIet: i3 2ro=p of F montDsO ta=rine:treate; ;iaIeti3 2ro=p of F montDsO ;iaIeti3 2ro=p of montDsO ta=rine:treate; ;iaIeti3 2ro=p of montDsO YitD 6 rats in ea3D 2ro=pWNnotDer 17 rats Yere 3Dosen Domeo3Drono=slL as n
6、ormal 3ontrol 2ro=pW LGHNCEK= XDe animals Yere raise; in separate 3a2esW XDeL Yere free to a33ess to foo; an; YaterO an; faste; for 1F Do=rs Iefore eZperimentW Htrep: tooto3in Yas =se; to in;=3e ;iaIetes mellit=s WDen Xes:Xape sDoYe; =rine 2l=3ose rea3De; more tDan(“)O an; Iloo; 2l=3ose 3on3entratio
7、n of 4eno=s Iloo; from tail meas=re; a19W? mmolT1Omo;els Yere estaIlisDe; s=33essf=llLW bZpressions of BNC mN an; protein Yere meas=re; YitD imm=noDisto3DemistrLOX:CCOestern Ilottin2 an; otDer te3Dni3al metDo;sWXDe effe3t of ta=rine on retinal ne=rons an; 2lial 3ells in rats YitD ;iaIetes mellit=s Y
8、as oIser4e;W L9I8CDH?CLGLG9KDBGK=bZpressionsofBNCmN an; protein BGKDMHK= cmm=noDisto3Demi3al analLsis sDoYe; tDat _Den rats s=ffere; from ;iaIetes mellit=s for 1 montDOta=rine 3an inDiIit tDe im: m=norea3ti4itL of BNCWitD tDe elon2ation of inter4ention time of ta=: rineOtDe imm=norea3ti4itL of BNC i
9、s Yeadene;WX:CC ;ete3tion_ Htartin2 from tDe Ie2innin2 of F montDsOtDe eZpression of BNCmN in ;iaIeti3 2ro=p Ie2an to in3reaseE ta=rine oI4io=slL ;oYn:re2=late; tDe eZ: pression of BNC mNW cn ta=rine:treate; ;iaIeti3 2ro=p of montDsO tDe eZpression of BNC Yas tDe stron2estW Den ;iaIeti3 rats Yere tr
10、eate; IL ta=rine for F montDsO tDe eZpression of BNC Yas ;e3rease;W ?C8?MDKIC8= Xa=rine 3an ;oYn:re2=late tDe eZpression of BNC m: N an; proteinOin;i3atin2 tDat it 3an prote3t retinal patDolo2i3al 3Dan2e in rats YitD ;iaIetes mellit=sW 5“ 65+ ,)-; ;(?;)=)-%0 .0)%0 :)A)00%B %)- DE2F %-C )= ?)- )- %=
11、G)=$ C)%A;=; D;00)=“8 )*+,-.+ /0,1*.2,- 32,-4. 1HHIJ*HK1LMN*I*O4PQ$)-%RSGGG8T.0=alitati4elL ;ete3te; at tDe ?Fn;Do=r after inie3tionWDen Xes:Xape sDoYe; =rine 2l=3ose rea3De; more tDan(“)O an; Iloo; 2l=3ose 3on3en: tration of 4eno=s Iloo; from tail meas=re; a 19W? mmolT1O mo;els Yere estaIlisDe; s=3
12、3essf=llLW Crimer sLntDesis_BNC primer_ N33or;in2 to literat=re fg O tDe len2tD of primer Yas F16 IpWBNC C1:7:NCN XCB NBN XCB CCN CCX NC:BNC CF:7:NCN XCN CNX CCX XBX BCX CC: internal referen3e $:a3tin primer_ R serial n=mIer:JM11SSV,tDe len2tD of XCC primer Yas ?9S Ip$:a3tin C1_7:XXB: XNNCCNNCXBBBNC
13、BNXNXBB:(FFSQFS? Ip)$:a3tin CF_ 中国临床康复第*H卷 第1L期FMM9QM?QFM出版 C*0,565 7+.8,29 +4 C90,0129 R5*2:090;2;0+,? A B+9C D E+C F!“! !“# $%? 2A3B C/#3 D;?G OF;8? I?J D=L;E; PQCNL I?J E?L;MQF D=JJ;ED ENL;? I?J JP;?L;D NMM0 3M ( CS E;D $ CU 4L=9QL; I?J ?DD;DV +?=K N9? =E; 8?D JP=M? $* - TZ$- C=Q ? ?D 9Q J;F MNNI
14、=T -V* CS EPNLNMNLC I?J ?DD;D R JQ8J;Q;QD T=Y; $* - TZ$( C=Q ?D 9Q $0( CU E;T -0( CU =JN9LN9F ?ENPN0 +;QT ?Q $* - TZ$- C=Q1 ?D $ CU DV3MT JP?;D = IP=L9NNR=Q ?D JQ9;L1 ?QD *- “U D;=N=;D I?FC; I?J ?DD;DV# BL;9?L? NM EaH3 JEL=9G-V( CS E; ?D 5 “T /H3 ?D -V(“T b=TN6D4:$7 I;L; ?DD;DV “ ?E 8QMM;L JN1 Q NM
- 配套讲稿:
如PPT文件的首页显示word图标,表示该PPT已包含配套word讲稿。双击word图标可打开word文档。
- 特殊限制:
部分文档作品中含有的国旗、国徽等图片,仅作为作品整体效果示例展示,禁止商用。设计者仅对作品中独创性部分享有著作权。
- 关 键 词:
- 牛磺酸 糖尿病 大鼠 视网膜 神经 胶质 纤维 酸性 蛋白 MRNA 及其 表达 影响
链接地址:https://www.31doc.com/p-3714628.html