全球疫苗市场研究报告 Vaccines 2010:the World Market.pdf
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1、Vaccines 2010 Rures adquireret umbraculi, etiam tremulus matrimonii libere senesceret app August 2010 Kalorama Information A division of MarketR 38 East 29th Street Sixth Floor New York, New York 10016 212.807 .2660 t 800.298.5603 t 212.807 .2676 f VACCINES 2010 THE WORLD MARKET A KALORAMA INFORMAT
2、ION MARKET INTELLIGENCE REPORT Vaccines 2010 has been prepared by Kalorama Information. We serve business and industrial clients worldwide with a complete line of information services and research publications. Kalorama Information Market Intelligence Reports are specifically designed to aid the act
3、ion-oriented executive by providing a thorough presentation of essential data and concise analysis. Author: Alison Sahoo : 38 East 29th Street New York, New York 10016 (800) 298-5699 Outside the U.S. (212) 807-2657 FAX: (212) 807-2676 http:/www.KaloramaI E-MAIL: COPYRIGHT 2010 Kalorama Information
4、a division of MarketR, Inc. Copyright 2010 Kalorama Information, LLC. Reproduction without prior written permission, in any media now in existence or hereafter developed, in whole or in any part, is strictly prohibited. Table of Contents iii Copyright 2010 Kalorama Information, LLC. Reproduction wit
5、hout prior written permission, in any media now in existence or hereafter developed, in whole or in any part, is strictly prohibited. TABLE OF CONTENTS CHAPTER ONE: EXECUTIVE SUMMARY1 THE GLOBAL VACCINES INDUSTRY .1 Scope and Methodology1 Overview .2 Pediatric Preventative Vaccines.3 The Market.5 Ad
6、ult Preventative Vaccines.8 The Market.9 Total Market.11 Issues and Trends.12 CHAPTER TWO: INTRODUCTION TO VACCINES15 A Brief History: The Development of Vaccines .16 The Immune Response.17 Mechanism of Action.17 Types of Vaccines.18 Attenuated (Weakened) Live Viruses18 Killed (Inactivated) Viruses.
7、20 Toxoid Vaccines20 Genetically Engineered/Modified Vaccines20 Subunit Vaccines .20 Conjugate Vaccines .21 DNA Vaccination.21 Vaccine Approval Process.22 CHAPTER THREE: PEDIATRIC PREVENTIVE VACCINES.27 Introduction27 Childhood Immunization in the United States29 Childhood Immunization Rates.29 Chal
8、lenges to the Vaccine Delivery System30 The Effect of U.S. Health Care Reform.31 Recommended Childhood Immunization Schedule.32 State Immunization Recommendations.40 United Nations Initiatives40 Pediatric Vaccine Products.41 BCG.42 Diphtheria, Tetanus, Pertussis, Hepatitis B and Polio.42 Diphtheria
9、44 Pertussis.44 Tetanus.45 Three: Pediatric Vaccines iv Copyright 2010 Kalorama Information, LLC. Reproduction without prior written permission, in any media now in existence or hereafter developed, in whole or in any part, is strictly prohibited. Hepatitis B .45 Poliomyelitis47 Haemophilus Influenz
10、ae Type B48 Hepatitis A.49 Measles, Mumps and Rubella50 Measles 51 Mumps .52 Rubella.53 Meningococcal Disease.54 Pneumococcal Conjugate.55 Rotavirus56 Varicella.58 Pediatric Vaccines in Development59 Cost of Vaccines in the United States.61 The World Market for Pediatric Preventive Vaccines61 Total
11、Market Size and Forecast.61 Hepatitis Vaccine Market67 Market Analysis.67 Leading Products and Competitors68 Haemophilus Influenzae Type B Vaccine Market.68 Market Analysis.69 Leading Products and Competitors70 Measles, Mumps and Rubella Vaccines70 Market Analysis.70 Combination Vaccines Market72 Ma
12、rket Analysis.73 Leading Products and Competitors74 Pneumococcal Vaccine75 Leading Products and Competitors76 Poliovirus Vaccine.77 Market Analysis.78 Leading Products and Competitors78 Varicella Vaccines.79 Market Analysis.80 Leading Products and Competitors81 Other Vaccines Market81 Market Analysi
13、s.81 Leading Products and Competitors83 CHAPTER FOUR: ADULT PREVENTIVE VACCINES85 Introduction85 Adult Vaccine-Preventable Diseases: Facts and Figures86 Global Influenza Surveillance Program 87 Recommendations for Adult Immunizations.88 WHO International Health Regulations.100 Table of Contents v Co
14、pyright 2010 Kalorama Information, LLC. Reproduction without prior written permission, in any media now in existence or hereafter developed, in whole or in any part, is strictly prohibited. Adult Vaccine Products.101 BCG.101 Cervical Cancer .102 Cholera.108 Diphtheria-Tetanus110 Hepatitis.111 Hepati
15、tis A.111 Hepatitis B .112 Influenza113 Japanese Encephalitis 119 Pneumococcal Disease.120 Rabies 121 Shingles .123 Typhoid Fever124 Yellow Fever .124 Adult Vaccines in Development125 The World Market for Adult Preventive Vaccines.127 Total Market Size and Forecast.127 Cervical Cancer Market.132 Mar
16、ket Analysis.133 Leading Products and Competitors134 Hepatitis Market 135 Market Analysis.136 Leading Products and Competitors137 Influenza Vaccine Market137 Market Analysis.139 Leading Products and Competitors141 Market Analysis.142 Leading Products and Competitors143 Travel, DT, and Miscellaneous
17、Vaccine Market.144 Market Analysis.145 Leading Products and Competitors147 CHAPTER FIVE: VACCINES MARKET SUMMARY.148 Trends Driving the Vaccines Market.148 Market Size and Forecast149 Vaccine Sales by Region.153 Vaccine Market Competitors.155 Pediatric Vaccines .158 Major Manufacturers Market Share
18、.159 Adult Vaccines.161 Major Manufacturers Market Share .161 CHAPTER SIX: ISSUES AND TRENDS.163 Vaccine Safety 163 Refusal to Immunize163 Three: Pediatric Vaccines vi Copyright 2010 Kalorama Information, LLC. Reproduction without prior written permission, in any media now in existence or hereafter
19、developed, in whole or in any part, is strictly prohibited. Obesity.165 Post-Licensure Surveillance 166 Vaccine Adverse Event Reporting System166 The Vaccine Safety Datalink Project.167 Phase IV studies.167 The Vaccine Injury Compensation Program .168 Countermeasures Injury Compensation Program168 W
20、orld Health Organization169 Other Initiatives.170 The Future of Vaccine Safety170 Vaccine Shortages171 Preventing Shortages in the Developed Countries.171 Financial incentives .172 Equitable pricing172 Vaccine stockpiles .173 Preventing Shortages in Developing Nations173 Vaccine bonds173 Preventing
21、Pandemics175 U.S. National Vaccine Plan.175 Vaccines and Bioterrorism176 Overview .176 Project Bioshield Act.176 National Bio and Agro-Defense Facility.178 Vaccine Treatment and Evaluation Units179 Anthrax179 Smallpox181 Tularemia.182 Viral Hemorrhagic Fevers .183 DNA Vaccination .184 Innovations in
22、 Vaccine Delivery Systems 185 Edible Vaccines.186 Mucosal Delivery.186 Intranasal Delivery.187 Vaccine Patches.189 Vaccine Chips189 Innovations in Vaccine Production 190 Tobacco Plants.190 Insects191 Nanoparticle Systems 192 CHAPTER SEVEN: COMPANY PROFILES .193 AlphaVax, Inc.193 History and Lines of
23、 Business.193 Strategic Alliances.194 Vaccine Products.195 Financial Information 195 Table of Contents vii Copyright 2010 Kalorama Information, LLC. Reproduction without prior written permission, in any media now in existence or hereafter developed, in whole or in any part, is strictly prohibited. B
24、avarian Nordic A/S196 History and Lines of Business.196 Strategic Alliances.196 Vaccine Products.197 Financial Information 197 Baxter Healthcare198 History and Lines of Business.198 Strategic Alliances.198 Vaccine Products.198 Financial Information 199 Bharat Biotech200 History and Lines of Business
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