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1、BRITISH STANDARD BS 5726-2: 1992 Microbiological safety cabinets Part 2: Recommendations for information to be exchanged between purchaser, vendor and installer and recommendations for installation Licensed Copy: sheffieldun sheffieldun, na, Mon Dec 04 15:54:06 GMT+00:00 2006, Uncontrolled Copy, (c)
2、 BSI BS 5726-2:1992 This British Standard, having been prepared under the direction of the Health Care Standards Policy Committee, was published under the authority of the Standards Board and comes into effect on 15 June 1992 BSI 12-1998 The following BSI references relate to the work on this standa
3、rd: Committee reference HCC/28 Draft for comment 91/52390 DC ISBN 0 580 20749 8 Committees responsible for this British Standard The preparation of this British Standard was entrusted by the Health Care Standards Policy Committee (HCC/-) to Technical Committee HCC/28, upon which the following bodies
4、 were represented: Association of the British Pharmaceutical Industry Association of Clinical Pathologists Association of Medical Microbiologists British Health and Safety Society British Laboratory Ware Association British Occupational Hygiene Society Chartered Institution of Building Services Engi
5、neers Department of Health Guild of Hospital Pharmacists Health and Safety Executive Institute of Animal Health Institute of Biology Institute of Hospital Engineering Institute of Medical Laboratory Sciences Institution of Mechanical Engineers Manufacturing Science Finance Medical Research Council M
6、inistry of Agriculture, Fisheries and Food Public Health Laboratory Service Royal College of Pathologists Coopted members Amendments issued since publication Amd. No.DateComments Licensed Copy: sheffieldun sheffieldun, na, Mon Dec 04 15:54:06 GMT+00:00 2006, Uncontrolled Copy, (c) BSI BS 5726-2:1992
7、 BSI 12-1998i Contents Page Committees responsibleInside front cover Forewordii 1Scope1 2Definitions1 3Exchange of information1 4Recommendations for installation2 Figure 1 Recommendations for minimum distances for avoiding disturbance to the safety cabinet and its operator7 Figure 2 Avoiding disturb
8、ances due to other personnel8 Figure 3 Air make-up and room ventilation systems9 Publication(s) referred toInside back cover Licensed Copy: sheffieldun sheffieldun, na, Mon Dec 04 15:54:06 GMT+00:00 2006, Uncontrolled Copy, (c) BSI BS 5726-2:1992 ii BSI 12-1998 Foreword This Part of BS 5726 was prep
9、ared under the direction of the Health Care Standards Policy Committee. Together with Parts 1, 3 and 4 it supersedes BS 5726:1979, which is withdrawn. Microbiological safety cabinets are also known as biological safety cabinets. The recommendations given in this Part of BS 5726 apply to contracts fo
10、r the supply and installation of microbiological safety cabinets which comply with Part 1 of this standard, and it is strongly recommended that this advice is followed. The Parts of this standard are as follows: Part 1: Specification for design, construction and performance prior to installation. Th
11、is Part is aimed primarily at manufacturers; Part 2: Recommendations for information to be exchanged between purchaser, vendor and installer and recommendations for installation. This Part is aimed primarily at installers; Part 3: Specification for performance after installation. This Part is aimed
12、primarily at those commissioning the cabinets; Part 4: Recommendations for selection, use and maintenance. This Part replaces the notes for users given in appendix G of the previous edition. A British Standard does not purport to include all the necessary provisions of a contract. Users of British S
13、tandards are responsible for their correct application. Compliance with a British Standard does not of itself confer immunity from legal obligations. Summary of pages This document comprises a front cover, an inside front cover, pages i and ii, pages 1 to 10, an inside back cover and a back cover. T
14、his standard has been updated (see copyright date) and may have had amendments incorporated. This will be indicated in the amendment table on the inside front cover. Licensed Copy: sheffieldun sheffieldun, na, Mon Dec 04 15:54:06 GMT+00:00 2006, Uncontrolled Copy, (c) BSI BS 5726-2:1992 BSI 12-19981
15、 1 Scope This Part of BS 5726 gives recommendations for the minimum information to be exchanged between the parties to contracts for the supply and/or installation of microbiological safety cabinets as specified in BS 5726-1. It also gives recommendations for installation including siting and provis
16、ion of extraction ductwork systems. NoteThe titles of the publications referred to in this standard are listed on the inside back cover. 2 Definitions For the purposes of this Part of BS 5726, the definitions given in BS 5726-1 apply. 3 Exchange of information 3.1 General It is strongly recommended
17、that for safety cabinets complying with BS 5726-1, the information given in 3.2 to 3.6 be exchanged between purchaser, vendor and installer. 3.2 Information to be supplied by the purchaser to the vendor The following information should be supplied by the purchaser to the vendor: a) any specific requ
18、irements which are evident from consideration by the purchaser of the guidance given in Part 4 of BS 5726; b) cabinet size and/or vendors reference number; c) services to be fitted; d) dimensions available for access to the building. 3.3 Information to be supplied by the purchaser to the installer.
19、The following information should be supplied by the purchaser to the installer. NOTE 1The installer may be the same party as the vendor. a) The following details of the siting of the safety cabinet(s). 1) Details of the building in which the safety cabinet is to be installed which may adversely affe
20、ct the performance of the cabinet, the location of the laboratory and the intended siting of the safety cabinet(s) within the laboratory. 2) The locations of doors, windows, fume cupboards, other safety cabinets, other laboratory furniture, ventilation grills, diffusers, or other air moving equipmen
21、t. 3) The absence, at the time of the survey, of any features listed in (2), which are planned but not installed. NOTE 2A site survey may be appropriate. b) General details of the intended method of supplying ventilation make-up air and of the existing room ventilation. c) The environmental requirem
22、ents of the laboratory including the following. 1) Overall noise levels, in particular if more than one cabinet is required either in the same room or other rooms in the same building. 2) Effects of any other cabinets/extraction units, air conditioning and ventilation systems that may contribute to
23、adverse air movements. 3) Room air volume flow rate and any pressure difference with respect to the outside atmosphere. d) The accommodation spaces, routes available and any specific design requirements for the safety cabinet extraction system. e) The locations and details of any existing mechanical
24、, electrical or other services to be utilized in connection with the complete safety cabinet installation. f) The following details of the safety cabinet(s). 1) Whether a facility to vary the set extraction volume flow rate is required and, if so, the range that is required. 2) Whether the safety ca
25、binet extraction system is to be for continuous or intermittent use. 3) The commissioning tests to be undertaken by the installers. (See BS 5726-3.) 3.4 Information to be supplied by the vendor to the purchaser The following information should be supplied by the vendor to the purchaser. a) Drawings
26、showing the overall external dimensions of the safety cabinet see also item i). b) An identification of all materials of construction used within the working area. c) The air extraction volume flow rates, corresponding face velocities and pressure drops across the safety cabinet with clean filters.
27、d) The safety cabinet type and serial number. e) All the information reported on successful completion of the test procedures as specified in BS 5726-1. f) Operating and maintenance instructions for all the equipment provided by the vendor, including the pressure loss characteristics of the safety c
28、abinet. g) Any specific limitations on use. Licensed Copy: sheffieldun sheffieldun, na, Mon Dec 04 15:54:06 GMT+00:00 2006, Uncontrolled Copy, (c) BSI BS 5726-2:1992 2 BSI 12-1998 h) Fan manufacturers performance curves for remote fans. These should include static pressure versus volume flow rate fo
29、r various voltage duty levels. i) The maximum external dimensions of the safety cabinet, and its dismantled components if appropriate, and the dimensions required for access into the building and internal access to where the safety cabinet is to be installed. 3.5 Information to be supplied by the ve
30、ndor to the installer The following information should be supplied by the vendor to the installer: a) fan data see 3.4 h); b) the air extraction volume flow rates, corresponding face velocities and pressure drops across the safety cabinet with clean filters; c) overall dimensions of the cabinet; d)
31、type and location of service outlets, mains supply cable and the exhaust ductwork take-off. 3.6 Information to be supplied by the installer to the purchaser The following information should be supplied by the installer to the purchaser: a) name and address of the installer; b) except for recirculati
32、ng type cabinets, drawings showing the complete final installation provided; c) nature of the materials of construction of the extraction system; d) any proposed amendments to the purchasers specification; e) results of the commissioning tests undertaken by the installer or his agent; f) operating a
33、nd maintenance instructions for the extraction system and for any room air make-up systems provided by the installer. 4 Recommendations for installation 4.1 Cabinets 4.1.1 The installation of cabinets and their commissioning will normally be the business of the supplier or an experienced agent. Loca
34、l engineers may need to be consulted to determine suitable routes to duct filtered air to the outside. 4.1.2 For containment level 3 laboratories where there is an installation problem because of difficulties in exhausting cabinet air to the outside, specialist advice should be obtained. 4.1.3 Opera
35、tor protection offered by a cabinet can be adversely affected by poor siting of the unit. It is important to avoid siting a microbiological safety cabinet in a thoroughfare or in line with a doorway or openable window. Preliminary airflow visualization tests may help to select the optimum position w
36、ithin a room. Performance is verified by conducting operator protection tests once the cabinet is in position and running (see BS 5726-3). In difficult conditions, it may be helpful to make a temporary installation of the cabinet in order to make these tests before the final installation. 4.1.4 The
37、siting of safety cabinets in laboratories should be considered at the initial stages of the planning of a new building or before modification of an existing building. If additional safety cabinets are required in an existing laboratory, the recommendations given in this clause also apply. The site s
38、elected should comply with the interrelated requirements for containment, extraction, room make-up air, ventilation and general environmental safety and comfort. The recommendations for siting given here are only intended to act as a guide to the avoidance of disturbances to the safety cabinet, its
39、operator and other personnel and to the avoidance of interference with escape routes, etc. No specific dimensions or planning arrangements can prospectively guarantee satisfactory performance of the cabinet in all cases. 4.1.5 If cabinets are joined together it is strongly recommended that the junct
40、ions should be airtight and should not put undue stress on the cabinets or any junction or adaptor pieces. Sealing gaskets or mating surfaces should not leave internal cavities or crevices. NOTEAttention should be paid to vibration as if it is excessive damage to seals and gaskets may occur. 4.1.6 T
41、o avoid disturbances to the safety cabinet and its operator, consideration should be given to the following. a) The distance from the plane of the aperture to any circulation space should be at least 1 000 mm, so as to preserve a zone undisturbed by anyone other than the operator see Figure 1 a). Li
42、censed Copy: sheffieldun sheffieldun, na, Mon Dec 04 15:54:06 GMT+00:00 2006, Uncontrolled Copy, (c) BSI BS 5726-2:1992 BSI 12-19983 b) The distance between the front aperture and a bench opposite it should ideally be at least 1 500 mm see Figure 1 b). However, containment performance is not likely
43、to be affected if this distance is reduced, for instance to enable an operator to use the bench behind, whilst working at the cabinet. In this case operator movement over a smaller distance may cause less air disturbance. With such procedures their effect on containment should be measured by relevan
44、t operator protection factor tests. c) There should be no opposing wall (or other obstruction likely to affect the airflow) within 2 000 mm of the front aperture see Figure 1 c). d) Safety cabinets should not be installed in positions where they are likely to be affected by other items of equipment.
45、 In particular the distance to the aperture of an opposing safety cabinet, fume cupboard, or the edge of a local exhaust ventilation outlet should be not less than 3 000 mm see Figure 1 d). e) Any room air supply diffuser should not be within 1 500 mm of the front aperture. If there are large number
46、s of safety cabinets in a laboratory this recommendation may be difficult to comply with, but where diffusers have to be placed in close proximity to a safety cabinet, their discharge velocities and therefore air handling rates will need to be low. f) A safety cabinet should not be positioned with e
47、ither side closer than 300 mm from a wall or similar obstruction see Figure 1 e). g) Large obstructions (e.g. an architectural column) projecting beyond the plane of the aperture should not be within 300 mm of the side of the safety cabinet see Figure 1 f) and Figure 1 g). h) Doorways should not be
48、within 1 500 mm of the aperture or within 1 000 mm of the side of the safety cabinet see Figure 1 h) except where a door includes air transfer grills in which case protection factor testing should be carried out to ascertain a suitable distance. 4.1.7 The position of a safety cabinet should satisfy
49、the spatial requirements (e.g. vision, lighting and convenience of access) of the operator and personnel working nearby. When a cabinet is installed on a bench top, the leading edge should be flush with or slightly overhanging the edge of the bench top. NOTE 1Typical problems and their solutions are illustrated in Figure 2. NOTE 2There should not be an open space between the leading edge of the cabinet and the front of the bench as this may create turbulence in front of the aperture. It also provides an obstacle which could adversely affect airf
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