The World Market for Pain Management Drugs and Devices.pdf
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1、World Market for Pain Management 5th THEWORLDMARKET FOR PAIN MANAGEMENTDRUGS AND DEVICES: AKALORAMA INFORMATION MARKETINTELLIGENCE REPORT The World Market for Pain Management Drugs and Devices has been prepared by Kalorama Information. We serve business and industrial clients worldwide with a comple
2、te line of information services and research publications. Kalorama Information Market Intelligence Reports are specifically designed to aid the action- oriented executive by providing a thorough presentation of essential data and concise analysis. Author: Mountaintop Medical Publication Date: May 2
3、013 COPYRIGHT 2013 Kalorama Information a division of MarketR, Inc. Table of Contents ii Copyright 2013 Kalorama Information Reproduction without prior written permission, in any media now in existence or hereafter developed, in whole or in any part, is strictly prohibited TABLE OF CONTENTS CHAPTER
4、ONE: EXECUTIVE SUMMARY 1? Introduction . 1? Scope and Methodology 2? Size and Growth of the Market 3? Issues and trends . 6? Leading Competitors . 7? CHAPTER TWO: INTRODUCTION AND OVERVIEW9? Definition of Pain . 9? Magnitude of Pain . 10? Physiology of Pain 11? Transduction 11? Transmission . 14? Pa
5、in Pathways 16? Types of Pain 18? Measurement of Pain 19? Treatment ModalitiesPharmacologic Management . 22? Analgesic Ladder 22? Step I Drugs 22? Step II Drugs . 23? Step III Drugs 25? Recommended Drug and Route 26? Administration Routes 26? Titration. 29? Treatment ModalitiesNon-pharmacologic Mana
6、gement . 30? Cognitive-Behavioral Therapies . 30? Multidisciplinary Pain Management . 31? Demographics . 32? CHAPTER THREE: TREATMENT MARKETS AND FORECASTS .33? Burn Pain . 33? Overview of Top Products 34? Opiate AgonistsNatural Alkaloids 34? Opiate AgonistsSemisynthetic Analogs 34? Opiate AgonistsS
7、ynthetic Compounds . 35? Market Size and Growth . 35? Table of Contents iii Copyright 2013 Kalorama Information Reproduction without prior written permission, in any media now in existence or hereafter developed, in whole or in any part, is strictly prohibited Markets by Region 38? Cancer Pain 41? B
8、reakthrough Cancer Pain 41? Overview of Top Products 42? Opiate Agonists- Natural Alkaloids 42? Opiate Agonists-Semisynthetic Analogs 43? Opiate Agonists- Synthetic Compounds . 43? Phenylpiperdine Compounds 43? New and/or Innovative Products . 44? Market Size and Growth . 45? Markets by Region 49? D
9、ental/Facial Pain . 52? Overview of Top Products 52? Opiate Agonists- Natural Alkaloids 53? Opiate Agonists-Semisynthetic Analogs 53? Opiate Agonists- Synthetic Compounds . 53? Opiate Agonist-Antagonists 54? Centrally-acting Synthetic Analgesic Compounds . 54? New Products 55? Market Size and Growth
10、 . 55? Markets by Region 58? Migraine Headache Pain . 61? Overview of Top Products 62? Selective Serotonin Agonists 62? New and/or Innovative Products . 62? Market Size and Growth . 63? Markets by Region 66? Musculoskeletal Pain . 69? Overview of Top Products 70? Phenylpiperidine Compounds . 71? Cox
11、-2 Inhibitors 71? Non-steroid Anti-inflammatory Drugs . 71? Opioid Agonists- Natural Alkaloids . 72? Hyaluronate Sodium Derivative . 72? New and/or Innovative Products . 73? Market Size and Growth . 74? Markets by Region 76? Neuropathic Pain . 79? Overview of Top Products 79? Antiseizure Drugs . 80?
12、 Opiate Agonists- Natural Alkaloids 80? Opiate Agonists-Semi-Synthetic Analogs 81? Phenylpiperidine Compounds . 81? Table of Contents iv Copyright 2013 Kalorama Information Reproduction without prior written permission, in any media now in existence or hereafter developed, in whole or in any part, i
13、s strictly prohibited New and/or Innovative Products . 81? Market Size and Growth . 83? Markets by Region 86? Obstetrical Pain . 89? Overview of Top Products 89? Opiate AgonistsSynthetic Compounds . 89? Opiate AgonistAntagonists . 90? Centrally Acting Synthetic Analgesic Compounds 90? Phenylpiperidi
14、ne Compounds . 91? Market Size and Growth . 91? Markets by Region 94? Pediatric Pain . 96? Overview of Top Products 97? Opiate Agonist-Antagonists 97? Indole Analogs 98? Opiate Agonists-Semisynthetic Analogs 98? Opiate Agonists- Natural Alkaloids 98? Market Size and Growth . 99? Markets by Region 10
15、2? Surgical and Trauma Pain 105? Overview of Top Products 105? Opiate AgonistsNatural Alkaloids 105? Opiate AgonistsSemisynthetic Analogs 106? Opiate AgonistsSynthetic Compounds . 106? Opiate AgonistAntagonists . 106? Centrally Acting Synthetic Analgesic Compounds 107? New and/or Innovative Product
16、Approvals . 107? Market Size and Growth . 110? Markets by Region 112? CHAPTER FOUR: DRUG DELIVERY .115? Oral Drug Delivery 117? Parenteral Drug Delivery 118? Transdermal . 119? Patient Controlled Analgesia 123? Intrathecal Implants 123? Electrotransport Drug Delivery . 124? CHAPTER FIVE: PAIN MANAGE
17、MENT DEVICES .125? Transcutaneous Electrical Nerve Stimulators 125? Table of Contents v Copyright 2013 Kalorama Information Reproduction without prior written permission, in any media now in existence or hereafter developed, in whole or in any part, is strictly prohibited Neuromuscular Stimulators .
18、 127? Spinal Cord Stimulators and Peripheral Nerve Stimulators 129? PCAs and Intrathecal Pain Pumps 130? Other Miscellaneous devices . 132? Cranial Electrotherapy Stimulation . 132? Electrothermal and Electromagnetic Therapy . 132? Thermography . 133? Market Size and Growth . 134? Markets by Region
19、137? CHAPTER SIX: ALTERNATE TREATMENT MODALITIES .140? Acupuncture . 140? ETPS Neuropathic Acupuncture . 141? Low Level Laser Light Therapy 142? Biofeedback 144? Relaxation . 146? Music and Pain Relief . 146? Wave Therapy 147? Acupressure . 148? Massage Therapy . 148? Natural Supplements in Pain Man
20、agement 149? Bioelectromagnetism . 152? Radiofrequency Technology . 153? Cryoablation 154? CHAPTER SEVEN: ISSUES AND TRENDS .155? Overview . 155? Barriers to Cancer Pain Management . 155? Education . 158? Chronic Pain and Work 159? Managed Care Pain Management . 161? The Fifth Vital Sign . 162? Use
21、of Psychopharmacology in Chronic Pain . 163? Use of Botulinum Neurotoxin . 166? Research and Development 167? Table of Contents vi Copyright 2013 Kalorama Information Reproduction without prior written permission, in any media now in existence or hereafter developed, in whole or in any part, is stri
22、ctly prohibited Dyloject . 167? Levadex . 168? MoxDuo IR . 168? Naproxcinod 168? Pennsaid 2% 168? Posidur 169? Remoxy . 169? Zelrix . 169? Zohydro ER . 169? ARC-4558 . 169? BEMA Buprenorphine . 170? NGX 1998 . 170? Sativex. 170? ATx08-001 170? The Elderly . 174? Oxycontin Issues 175? Constant Pain P
23、henomenon 177? Tylenol and Liver Damage . 178? Pain Medication Treatment Confusion . 180? Transporter Discovery 182? Marijuana and Pain Control 184? Abuse-Deterrent Painkillers . 186? Drug Abuse and Pain Control 186? CHAPTER EIGHT: MARKET SUMMARY .188? Total Market Size and Forecast . 189? Total Mar
24、ket Revenues by Region . 195? Competitor Analysis 198? CHAPTER NINE: CORPORATE PROFILES 203? Abbott Laboratories 204? Actavis, Inc (formerly Watson Pharmaceuticals, Inc.) 206? AstraZeneca plc. 209? Baxter International, Inc. . 211? BioDelivery Sciences International (BDSI) . 214? Boehringer Ingelhei
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