The World Market for Transdermal Drug Delivery.pdf
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1、Transdermal Drug Delivery September 2012 Kalorama Information A division of MarketR 38 East 29th Street Sixth Floor New York, New York 10016 212.807 .2660 t 800.298.5603 t 212.807 .2676 f Copyright 2012 Kalorama Information Reproduction without prior written permission, in any media now in existenc
2、e or hereafter developed, in whole or in any part, is strictly prohibited. DRUG DELIVERY MARKETS TRANSDERMAL AND TRANSMUCOSAL DELIVERY SYSTEMS A KALORAMA INFORMATION MARKET INTELLIGENCE REPORT Transdermal and Transmucosal Drug Delivery has been prepared by Kalorama Information, a division of MarketR
3、, Inc. We serve life sciences clients in the United States and abroad with a complete line of information services and research publications. Kalorama Information Market Intelligence Reports are specifically designed to aid the action-oriented executive by providing a thorough presentation of essent
4、ial data and concise analysis. Author: Mountaintop Medical LLC Publication Date: 38 East 29th Street New York, New York 10016 (800) 298-5699 Outside the U.S. (212) 807-2657 FAX: (212) 807-2676 http:/www.KaloramaI E-MAIL: Copyright 2012 Kalorama Information Reproduction without prior written permiss
5、ion, in any media now in existence or hereafter developed, in whole or in any part, is strictly prohibited. Copyright 2012 Kalorama Information Reproduction without prior written permission, in any media now in existence or hereafter developed, in whole or in any part, is strictly prohibited. TABLE
6、OF CONTENTS CHAPTER ONE: EXECUTIVE SUMMARY 1 Market Drivers 2 Market Size and Growth . 3 Total Transdermal/Transmucosal Drug Delivery Market 3 Transdermal/Transmucosal Drug Delivery Only Market . 4 Competitive and Market Analysis . 4 CHAPTER TWO: INTRODUCTION AND OVERVIEW7 Scope and Methodology 7 Re
7、asons for Transdermal/Transmucosal Drug Delivery Systems 8 Phases of Drug Action . 9 Transdermal drug Delivery . 10 History of Transdermal Drug Delivery . 10 Advantages of Transdermal Drug Delivery 14 Disadvantages of Transdermal Drug Delivery . 15 Transdermal Patch (Passive) Drug Delivery . 15 Tran
8、sfersomes . 21 Medicated Tattoos . 21 Crystal Reservoir Technology 22 Active Transdermal Drug Applications 22 Electrotransport Drug Delivery . 24 Iontophoresis . 25 Reverse Iontophoresis . 26 Sonophoresis 27 Photomechanical Waves . 27 Transmucosal Drug Delivery 27 Buccal Drug Delivery 32 Vaginal Dru
9、g Delivery 35 CHAPTER THREE: TRENDS AND DEVELOPMENTS 37 Novel Transdermal Approvals 37 Innovations in Transdermal Drug Delivery 38 Adhesive Technology and Issues 39 Adhesive Market Issues 40 Generic Transdermal Study Design Guidelines . 42 Biotechnological Issues 42 The Market for Transdermal/Transm
10、ucosal Delivery Systems Copyright 2012 Kalorama Information Reproduction without prior written permission, in any media now in existence or hereafter developed, in whole or in any part, is strictly prohibited. iv Developments in Insulin Delivery 45 New Developments in Hormone Drug Delivery . 46 New
11、Mucosal/Buccal Delivery Systems . 48 Other New Drug Delivery Systems 49 Microneedle-Assisted Transdermal Drug Delivery . 53 Controlled Thermal Energy Technology 54 New Ultrasound Technology 54 Transdermal Products in Development 55 CHAPTER FOUR: MARKET SIZE AND GROWTH 59 The Total Transdermal/Transm
12、ucosal Drug Delivery Market 59 Transdermal/Transmucosal Delivery Technology Only Market 68 CHAPTER FIVE: COMPETITIVE ANALYSIS .73 Competitive Landscape 73 Emerging Participants 75 Market Analysis 77 CHAPTER SIX: COMPANY PROFILES 79 3M Pharmaceuticals . 80 Access Pharmaceuticals, Inc. . 82 Acrux Limi
13、ted . 83 ALZA Corporation . 85 Antares Pharma, Inc. 88 Apricus BioSciences 90 Aveva Drug Delivery Systems 92 Generex Biotechnology Corporation . 93 Inovio Pharmaceuticals, Inc. . 95 Labtec GmbH 96 Lohmann Therapy-Systems Corp (LTS Lohmann Therapie Systeme AG) 98 NITTO DENKO CORPORATION 99 Noven Phar
14、maceuticals, Inc. 102 Pantec Biosolutions AG 103 Tapemark . 104 Table of Contents Copyright 2012 Kalorama Information Reproduction without prior written permission, in any media now in existence or hereafter developed, in whole or in any part, is strictly prohibited. v TEVA Pharmaceutical Industries
15、 Ltd. 106 Zosano Pharma 108 TABLE OF EXHIBITS CHAPTER TWO: INTRODUCTION AND OVERVIEW Table 2-1: Select Leading Transdermal Delivery-Based Products . 13 CHAPTER THREE: TRENDS AND DEVELOPMENTS Table 3-1: Selected Transdermal Products in Development . 56 CHAPTER FOUR: MARKET SIZE AND GROWTH Table 4-1:
16、The Worldwide Market for Transdermal/Transmucosal Drug Delivery Technology and Pharmaceuticals 2010-2017 60 Figure 4-1: The Worldwide Market for Transdermal/Transmucosal Drug Delivery Technology and Pharmaceuticals 2010-2017 61 Table 4-2: The Worldwide Market for Pharmaceuticals Utilizing Transderma
17、l/Transmucosal Drug Delivery Systems by Type 20102017 63 Figure 4-2: The Worldwide Market for Pharmaceuticals UtilizingTransdermal/ Transmucosal Drug Delivery Systems Revenues by Type 20102017 64 Table 4-3: The Worldwide Market for Pharmaceuticals Utilizing Transdermal/Transmucosal Drug Delivery Tec
18、hnologies Market Share by Type 2010-2017 65 Figure 4-3: Transdermal Drug Delivery Market by Disease Treated (Cardiovascular, Hormones, Pain Management, Smoking Cessation) 66 Table 4-4: The Worldwide Market for Transdermal/Transmucosal Drug Delivery Systems by Region (United States, Europe, Japan, RO
19、W) 20102017 67 Table 4-5: The Worldwide Market for Transdermal/Transmucosal Drug Delivery Systems by Pharmaceutical and Drug Delivery Component 2010-2017 69 Table 4-5: The Worldwide Market for Transdermal/Transmucosal Drug Delivery Systems Distribution of Revenue by Pharmaceutical and Drug Delivery
20、Component 2010-2017 69 The Market for Transdermal/Transmucosal Delivery Systems Copyright 2012 Kalorama Information Reproduction without prior written permission, in any media now in existence or hereafter developed, in whole or in any part, is strictly prohibited. vi Figure 4-4: The Worldwide Marke
21、t for Transdermal/Transmucosal Drug Delivery Systems Distribution of Revenue by Pharmaceutical and Drug Delivery Component 2010-2017 70 Figure 4-5: The Worldwide Market for Transdermal/Transmucosal Drug Delivery Systems Distribution of Revenue by Pharmaceutical and Drug Delivery Component 2012 . 71
22、Figure 4-6: The Worldwide Market for Transdermal/Transmucosal Drug Delivery Systems Distribution of Revenue by Pharmaceutical and Drug Delivery Component 2017 . 72 CHAPTER FIVE: COMPETITIVE ANALYSIS .73 Table 5-1: Leading Suppliers of Transdermal/Transmucosal Drug Delivery Technology . 77 Copyright
23、2012 Kalorama Information Reproduction without prior written permission, in any media now in existence or hereafter developed, in whole or in any part, is strictly prohibited. CHAPTER ONE Executive Summary It is anticipated that the transdermal/transmucosal drug delivery market will continue to grow
24、. The market is expected to be driven by various factors including the loss of patent protection for blockbuster drugs and the need to avoid the first pass effects of oral drug delivery. Additionally, with an added focus on active transdermal technologies, new applications will likely cause a resurg
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