胃癌治疗进展PPT演示课件.pptx

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1、胃癌治疗进展胃癌治疗进展-2016 ASCOThis paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT8

2、9C51 microcontroller and DS18B20 temperature sensor.Where we are standing 过去影响巨大的进展 This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and singl

3、e chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.北美欧洲亚洲发病率发病率 70%的新发病例来自发展中国家的新发病例来自发展中国家 约约50%来自东亚地区（主要来自中国）来自东亚地区（主要来自中国）好发部位好发部位西方国家：近端胃癌（近端胃小弯、贲门、胃食管结合部）日本和世界其他国家：远端胃癌（胃窦、胃体）西方国家：近端胃癌（近端胃小弯、贲门、胃食管结合部）日本和世界其他国家：远端胃癌（胃窦、胃体）胃癌的流行病学存在地

4、区差异This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontrolle

5、r and DS18B20 temperature sensor.中国最新肿瘤登记年报显示：胃癌发病率、死亡率均位居我国恶性肿瘤前三位中国肿瘤登记年报2012This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chi

6、p microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.分期5年生存率1IA71%IB57%IIA46%IIB33%IIIA20%IIIB14%IIIC9%IV4%各期胃癌的5年生存率1,2胃癌的预后1.The survival rates that follow come from the National Cancer Institutes SEER database 1991-20002.Kulig J,et al.Langen

7、becks Arch Surg.2008;393(1):37-43This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the sys

8、tem are AT89C51 microcontroller and DS18B20 temperature sensor.胃癌的治疗模式存在地区差异北美手术+术后放化疗或单一口服化疗欧洲术前化疗+手术+术后化疗亚洲D2根治术+术后辅助化疗INT0116ACTS-GCMAGICACTS-GCCLASSIC手术方式不同，复发率不同，辅助治疗的模式不同This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperat

9、ure measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.目前胃癌治疗分期为依据转移性胃癌（IV期）二线/多线治疗手术辅助化疗早期胃癌（I期）新辅助治疗化疗/放疗手术复发局部进展期胃癌（II-III期）一线治疗辅助治疗化疗/放疗复发死亡治愈胃癌确

10、诊患者活检+病理胃癌疑似患者辅助检查肿瘤标记物，影像学检查，胃镜85%40%45-60%局部进展期胃癌/转移性胃癌经化疗或靶向治疗后可能重新获得手术机会This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip m

11、icrocomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.手手术（新）（新）辅助化助化疗晚期系晚期系统治治疗Where we are looking for 2015 ASCO 新进展This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature mea

12、surement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.Songun I et al.Lancet Oncol 2010Dutch试验的15年随访结果D2相比D1手术能显著提高长期生存率，降低胃癌相关死亡率15年年OSThis paper mainly in

13、troduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperatu

14、re sensor.D2还是D3？JCOG9501：OS5-ys OSD2 69.2%D3 70.3%HR=1.03 P=0.85 N Engl J Med 2008;359:453-462.This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B

15、20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.微创还是开腹？姑息手术的作用？JCOG 0912CLASS-01REGATTAThis paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measure

16、ment and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.2015 ASCO 胃癌外科手术治疗进展Abstract 4017A phase III study of laparoscopy-assisted vs open distal gastrectomy wit

17、h nodal dissection for clinical stage IA/IB gastric cancer(JCOG0912):Analysis of the safety and short-term clinical outcomes.Masakazu Takagi,etal腹腔镜辅助与开放远端胃切除术淋巴结清扫对临床IA/IB期胃癌的III期研究（JCOG 0912）：安全性和短期临床疗效分析 This paper mainly introduces the design of an intelligent temperature control system which re

18、alizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.JCOG 0912 试验设计入组IA或IB期未进行过放疗或化疗1EP：RFS2EP：OS，LADG完成率，完成率，AE，QOL

19、转至开腹比例，转至开腹比例2010-2013This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT

20、89C51 microcontroller and DS18B20 temperature sensor.JCOG 0912 结果1This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomput

21、er.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.JCOG 0912 结果2This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature

22、 sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.JCOG 0912 结果3住院期间，3级或4级非血液学不良事件无明显差异3级或4血清AST、ALT升高的比例较高（LADG vs ODG 16.4%vs 5.3%，P 0.001）This paper mainly introduces the design of an intelligent temperature c

23、ontrol system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.JCOG 0912 结论虽然血清AST/ALT升高应注意，本试验证实，有资质的外科

24、医生进行LADG，安全性和短期临床疗效上不低于ODG。如果计划到2018年LADG的基础分析OS不劣于ODG，LADG将成为IA/IB胃癌的另外一种可选治疗手段This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single ch

25、ip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.2015 ASCO 胃癌外科手术治疗进展Abstract 4032Laparoscopic D2 distal gastrectomy versus conventional open surgery for advanced gastric cancer:The safety analysis from a multicenter prospective randomized

26、 controlled trial in China(CLASS-01 Trial).Yanfeng Hu,etal局部晚期胃癌，腹腔镜D2远端胃切除术对比传统开腹手术的安全性分析中国，多中心，前瞻性临床试验This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sens

27、or DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.CLASS-01 试验设计临床分期T2-4a，N0-3，M0期远端胃癌 15位有资质的外科医生，14个中心（2012-2014）R腹腔镜D2远端胃大部切除术（LG）N=308开腹胃癌D2根治术组（OG）N=299术后30天内的并发症死亡率PhaseIII主要研究终点：3y-DFS计划中的中期分析（n=607）截至2014年12月，

28、全部1056例入组完成在上周巴西IGCC中口头报告This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are

29、AT89C51 microcontroller and DS18B20 temperature sensor.CLASS-01 结果1This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcompu

30、ter.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.CLASS-01 结果2This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature

31、 sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.CLASS-01 结果3This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and contr

32、ol by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.CLASS-01 结论试验结果：主要研究结果尚在统计中。两组的术后并发症及死亡率均没有统计学差异。LG组患者转为开腹手术的患者比例为4.5%。试验结论：有经验的外科医生行腹腔镜D2远端胃大部切除术是安全的。This paper mainl

33、y introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 tempe

34、rature sensor.2015 ASCO 胃癌外科手术治疗进展Abstract 200Randomized controlled trial of comparing gastrectomy(Gx)plus chemotherapy(CTX)with CTX alone in advanced gastric cancer(AGC)with a single non-curable factor:JCOG 0705/KGCA01 study(REGATTA)Han-Kwang Yang,et al.对有单一不可切除因素的晚期胃癌患者：胃切除术加化疗与单独化疗的随机对照试验This pap

35、er mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B

36、20 temperature sensor.REGATTA研究设计This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the sys

37、tem are AT89C51 microcontroller and DS18B20 temperature sensor.REGATTA 结果1This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip mic

38、rocomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.REGATTA 结果2This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital tempe

39、rature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.REGATTA 结果3This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and

40、control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.REGATTA 安全性This paper mainly introduces the design of an intelligent temperature control system which realizes the

41、 function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.REGATTA 亚组分析This paper mainly introduces the design of an intelligent tem

42、perature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.REGATTA 亚组分析This paper mainly i

43、ntroduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperat

44、ure sensor.REGATTA 结论试验结果：胃切除术并未提高AGC患者的OS.胃切除术是安全的，未发现死亡事件，但发现与迟发AE相关。胃切除组有更高发和更严重的不良反应，特别是上部切除或全胃切除者。亚组分析显示远端胃切除术患者OS可能会获益。试验结论：对有不可切除的单因素晚期胃癌患者，化疗仍是标准治疗手段。不推荐减瘤手术。This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measur

45、ement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.2015 ASCO 胃癌外科手术治疗进展小结JCOG 0912研究有资质的外科医生进行LADG，安全性和短期临床疗效上不低于ODG。LADG将成为IA/IB胃癌的另外一种可选治疗手段。CLASS-01 Tri

46、al研究有经验的外科医生行腹腔镜D2远端胃大部切除术是安全的。REGATTA研究对于AGC患者，手术加化疗相比于单独化疗，并不能延长OS。化疗仍是AGC患者的标准治疗方案。This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and sin

47、gle chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.手手术（新）（新）辅助助Where we are looking for 2015 ASCO 新进展辅助助This paper mainly introduces the design of an intelligent temperature control system which realizes the function of temperature mea

48、surement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.2015 ASCO 新辅助化疗进展Abstract 4061NeoFLOT II:Multicenter phase II study with short time neoadjuvant chemo

49、therapy(stNACT)with 5-FU,FA,oxaliplatin,and docetaxel in rectable adenocarcinoma of the gastresophageal junction and gastric adenocarcinoma(T3,T4,and/or LN)with high R0 resection rate over 91.5%.Karsten Ridwelski,et al.FLOT短时新辅助化疗在可切除G/GEJ腺癌（T3,T4和/或LN）中的应用多中心II期研究This paper mainly introduces the de

50、sign of an intelligent temperature control system which realizes the function of temperature measurement and control by using single bus digital temperature sensor DS18B20 and single chip microcomputer.The core components of the system are AT89C51 microcontroller and DS18B20 temperature sensor.NeoFL